Meridia is indicated for people who need to lose 30 pounds or more depending on height, and should be used in conjunction with a reduced-calorie diet.Meridia is not for everyone, including people who are allergic to any of the ingredients of Meridia, those with anorexia nervosa, bulimia nervosa, or who are taking monoamine oxidase inhibitors (MAOIs) or weight loss medications to control your appetite.Meridia substantially increases blood pressure or heart rate in some patients and should not be given to patients with uncontrolled or poorly controlled hypertension, history of heart disease, stroke, severe liver or kidney disease, pregnant women or nursing mothers. Meridia should be used cautiously in patients with a history of hypertension, glaucoma, seizures, or mild to moderate kidney disease. All patients being treated with Meridia should see their doctor as directed for regular monitoring of blood pressure and heart rate.It is important that you tell your healthcare provider about all current and past medical problems. Do not take other medicines with Meridia unless your doctor has told you that it is okay to do so. Talk to your doctor about all medications (including prescriptions for depression, and those which may increase risk of bleeding), over-the-counter medicines, such as cough and cold, and herbal products that you are currently taking or have recently taken.Meridia is a controlled substance (CIV). This means that Meridia can be a target for people who abuse prescription medicines.The most common side effects include headache, dry mouth, anorexia, constipation, and insomnia.